Introduction: Open appendectomy was first introduced by McBurney and has been considered as the treatment of choice for more than a century for acute appendicitis. However, recently, laparoscopic appendectomy (LA) has become the popular method of treatment for patients with acute appendicitis. Aims and objectives: The aim of this study was to compare results of LA with mini-incision open appendectomy in terms of various parameters such as time taken to complete the procedure, postoperative pain, need for analgesia, hospital stay, days to return to normal activity cosmetic results, and complications. Material and methods: This study was a prospective study conducted in the Department of Surgery, SKIMS Medical College, Bemina, Srinagar, Jammu and Kashmir, India, from July 2017 to June 2019. All patients more than 14 years in age admitted in the accident emergency department of the hospital with a clinical diagnosis of acute appendicitis were included in the study. Results and observations: Total number of patients studied was 101 and were randomly taken either for mini-incision open appendectomy or laparoscopic surgery. The two groups were comparable with respect to age and sex distribution with no statistically significant difference. The average operative time in mini-incision appendectomy (MIA) group was 32.7 ± 2.52 (30–35 years of age) compared to 26.9 ± 2.46 (24–30 years of age) in laparoscopic group, which was statistically significant. The patients with laparoscopic surgery experienced less pain and had less postoperative wound infection as compared to MIA group with p <0.001, which was statistically significant. Conclusion: Comparison done on the basis of statistical results between the two groups was suggestive of superiority of LA over MIA.
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