Background: After cesarean section, hysterectomy is the second most common procedure performed in the OBGY department. In this study, we analyzed the safety and complications of total laparoscopic hysterectomy (TLH) at our tertiary care center. Total laparoscopic hysterectomy is the preferred procedure over the laparotomy because of higher feasibility and lower postoperative complications. Materials and methods: This is a retrospective cohort study conducted on 200 patients who underwent TLH due to various benign gynecological conditions from January 1, 2017 to July 31, 2022. The statistical analysis was done using EPIINFO software. Results: The mean age of the women undergoing TLH at our center was 42 years. About 52% of the women were having parity 2, 43% were having a uterine size between 6 and 12 weeks. The most common symptom and indication for TLH were heavy menstrual bleeding (75.5%) and AUB L (leiomyoma) is about 49%, respectively. The average blood loss in the study was 150 mL. The mean duration of surgery was 50 minutes. The mean duration of hospital stay was 3 days. And 4% of the patients had intraoperative complications, 9% had postoperative complications which were identified and managed successfully. Conclusion: Laparoscopic gynecological surgeries are safe procedures in terms of feasibility in obese patients, minimal blood loss, and postoperative complications in patients with benign uterine etiology. Greater technical challenges and advanced equipment with long learning curve make it difficult for all surgeons to practice it.