World Journal of Laparoscopic Surgery

Register      Login

VOLUME 16 , ISSUE 1 ( January-April, 2023 ) > List of Articles

Original Article

Laparoscopic Cholecystectomy in Gangrenous Cholecystitis

Preetinder Brar, Hemant Yadav, Saraansh Bansal, Jai Dev Wig

Keywords : Cholecystitis, Gangrenous, Laparoscopic

Citation Information : Brar P, Yadav H, Bansal S, Wig JD. Laparoscopic Cholecystectomy in Gangrenous Cholecystitis. World J Lap Surg 2023; 16 (1):25-28.

DOI: 10.5005/jp-journals-10033-1562

License: CC BY-NC 4.0

Published Online: 05-09-2023

Copyright Statement:  Copyright © 2023; The Author(s).


Abstract

Introduction: Gangrenous cholecystitis (GC) is difficult to diagnose preoperatively. A delay in diagnosis leads to increased complications. A high index of suspicion followed by early surgery leads to increased chances of laparoscopic cholecystectomy with decreased morbidity and early discharge. The aim of the study was to study the demographics, contrast-enhanced computerized tomography (CECT) and magnetic resonance imaging (MRI) findings, type of procedure (laparoscopic/open), and the outcome of the patients. Materials and methods: A retrospective study was undertaken on GC patients. Patients were divided into three groups depending upon the type of surgery (LC, OC, LC-OC). Patient demographics, comorbidities, preoperative biochemical, CECT, MRI findings, time taken from admission to surgery, type of surgery, post-op complications, and length of stay were compared. Results: During a 5-year period, a total of 55 patients were diagnosed with GC. Of these cases, 47.27% underwent laparoscopic cholecystectomy (LC), 41.82% were treated with OC, and the remaining 10.91% had a combination of LC and OC. The median age of the patients was 58.12 ± 16.66 years, 65.65 ± 11.13, 58.16 ± 12.79 years in LC, OC, LC-OC groups respectively. The male to female ratio was 1.4:1. Approximately 45.45% of the individuals had hypertension, while 41.81% were diagnosed with diabetes. Additionally, 16.36% of the patients were found to have coronary artery disease (CAD), and 14.54% were undergoing antiplatelet therapy. Moreover, leukocytosis was observed in 40% of the patient cases. The conversion rate from laparoscopic procedure to open procedure was 18.75%. Postoperative morbidity was seen in 18.18% of patients. Average hospital and ICU stay in the LC group was the shortest (3.76 ± 1.94 days, 0.53 ± 1.38 days respectively). Hospital and ICU stay in the OC group was 10.8 ± 5.76 and 2.43 ± 5.35 days respectively. The average stay of the LC-OC group in the hospital and ICU was 9 ± 6.75 and 3.5 ± CECT 68 days. The p-value for hospital and ICU stay was 0.0001 and 0.0179 respectively. Conclusion: A high index of suspicion, and increased use of CECT and MRI in suspected cases followed by early LC leads to favorable outcomes in GC.


HTML PDF Share
  1. Bourikian S, Anand RJ, Aboutanos M, et al. Risk factors for acute gangrenous cholecystitis in emergency general surgery patients. Am J Surg 2015;210(4):730–733. DOI: 10.1016/j.amjsurg.2015.05.003.
  2. Fang R, Yerkovich S, Chandrasegaram M. Pre-operative predictivefactors for gangrenous cholecystitis at an Australian quaternary cardiothoracic centre. ANZ J Surg 2022;92(4):781–786. DOI: 10.1111/ans.17410.
  3. Onder A, Kapan M, Ulger BV, et al. Gangrenous cholecystitis: Mortality and risk factors. Int Surg 2015;100:254–260. DOI: 10.9738/INTSURG-D-13-00222.1.
  4. Wu B, Buddensick TJ, Ferdosi H, et al. Predicting gangrenous cholecystitis. HPB (Oxford) 2014;16(9):801–806. DOI: 10.1111/hpb.12226.
  5. Ganpathi AM, Speicher PJ, Englum BR, et al. Gangrenous cholecystitis: A contemporary review. J Surg Res 2015;197(1):18–24. DOI: 10.1016/j.jss.2015.02.058.
  6. Chawla A, Bosco JI, Lim TC, et al. Imaging of acute cholecystitis and cholecystitis-associated complications in emergency setting. Singapore Med J 2015;56(8):438–443 quiz 444. DOI: 10.11622/smedj.2015120.
  7. Choi SB, Han HJ, Kim CY, et al. Early laparoscopic cholecystectomy is the appropriate management for acute gangrenous cholecystitis. Am Surg 2011;77(4):401–406. PMID: 21679545.
  8. Falor AE, Zobel M, Kaji A, et al. Admission variables predictive of gangrenous cholecystitis. Am surg 2012;78(10):1075–1078. PMID: 23025944.
  9. Wilson AK, Kozol RA, Salwen WA, et al. Gangrenous cholecystitis in an urban VA hospital. J Surg Res 1994;56(5):402–404. DOI: 10.1006/jsre.1994.1064.
  10. Sahu S, Agarwal S, Sachan P. Intraoperative difficulties in laparoscopic cholecystectomy. Jurnalul dr Chirurgie (Iasi) 2003;9(2):2–5. DOI:10.7438/1584-9341-9-2-5.
  11. Nikfarjam M, Niumsawatt V, Sethu A, et al. Outcomes of contemporary management of gangrenous and non-gangrenous acute cholecystitis. HPB (Oxford) 2011;13(8):551–558. DOI: 10.1111/j.1477-2574.2011.00327.x.
  12. Merriam LT, Kanaan SA, Dawes LG, et al. Gangrenous cholecystitis: Analysis of risk factors and experience with laparoscopic cholecystectomy. Surgery 1999;126(4):680–685; Discussion 685–686. PMID: 10520915.
  13. Chaudhry S, Hussain R, Rajasundaram R, et al. Gangrenous cholecystitis in an asymptomatic patient found during an elective laparoscopic cholecystectomy: A case report. J Med Case Rep 2011;5:199. DOI: 10.1186/1752-1947-5-199.
  14. Dhir T, Schiowitz R. Old man gall bladder syndrome: Gangrenous cholecystitis in the unsuspected patient population. Int J Surg Case Rep 2015;11:46–49. DOI: 10.1016/j.ijscr.2015.03.057.
  15. Ambe PC, Köhler L. Is the male gender an independent risk factor for complication in patients undergoing laparoscopic cholecystectomy for acute cholecystitis? Int Surg 2015;100(5):854–859. DOI: 10.9738/INTSURG-D-14-00151.1.
  16. Saber SAAF, Elshoura AAAF, Abd-Raboh OH. Laparoscopic cholecystectomy of gangrenous cholecystitis safety and feasibility. Adv Surg Sci 2018;6(1):16–19. DOI: 10.11648/j.ass.20180601.13.
  17. Yacoub WN, Petrosyan M, Sehgal I, et al. Prediction of patients with acute cholecystitis requiring emergent cholecystectomy: A simple score. Gasroenterol Res Pract 2010;2010:901739. DOI: 10.1155/2010/901739.
  18. Hunt DR, Chu FC. Gangrenous cholecystitis in the laparoscopic era. Aust N Z J Surg 2000;70(6):428–430. DOI: 10.1046/j.1440-1622.2000.01851.x.
  19. Fagan SP, Awad SS, Rahwan K, et al. Prognostic factors for the development of gangrenous cholecystitis. Am J Surg 2003;186(5):481–485. DOI: 10.1016/j.amjsurg.2003.08.001.
  20. Surekha B, Rastogi A, Mukund A, et al. Gangrenous cholecystitis: analysis of imaging findings in histopathologically confirmed cases. Indian J Radiol Imaging 2018;28(1):49–54. DOI: 10.4103/ijri.IJRI_421_16.
  21. Chang WC, Sun Y, Wu EH, et al. CT findings for detecting the presence of gangrenous ischemia in cholecystitis. AJR Am J Roentgenol 2016;207(2):302–309. DOI: 10.2214/AJR.15.15658.
  22. Habib FA, Kolachalam RB, Khilnani R, et al. Role of laparascopic cholecystectomy in the management of gangrenous cholecystitis. Am J Surgery 2001;181(1):71–75. DOI: 10.1016/s0002-9610(00)00525-0.
  23. Girgin S, Gedik E, Tacyildiz IH, et al. Factors affecting morbidity and mortality in gangrenous cholecystitis. Acta Chir Belg 2006; 106(5):545–549. DOI: 10.1080/00015458.2006.11679949.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.