Introduction: The gold standard surgical procedure for treating cholelithiasis has been cholecystectomy. The situation with regard to surgical management of gallstones (GS) has significantly changed with the advent of laparoscopic cholecystectomy. This laparoscopic approach has several theoretical advantages, such as lower hospitalization and recovery costs, pain reduction, avoiding large incisions for better cosmetic results, and quicker return to work following surgery. Recent trials indicate a rise in occurrence of operative complications, particularly common bile duct (CBD) injury, despite early promising results. Laparoscopy use is further restricted by costly equipment, specialized training requirements, and a protracted learning curve. Materials and methods: This study was done at MGM medical college and Hospital, Navi Mumbai, from August 2010 and September 2012. Fifty patients admitted in OPD and emergency department from the Department of Surgery fulfilling the inclusion and exclusion criteria were included in the study. After complete investigations and with written informed valid consent, patients were subjected to laparoscopic cholecystectomy. The duration of postoperative pain from the day of surgery including mild pain to severe pain and the number of postoperative days with postoperative pain and number of days of analgesia required were noted and documented for further comparison. Results: Time taken for operation was significantly longer in the laparoscopic cholecystectomy group (p < 0.001). Postoperative stay is less and faster recovery requirement of analgesics is also less in laparoscopic cholecystectomy group of patients. Conclusion: Laparoscopic procedure can be feasible in patients with acute cholecystitis with steep learning curve. Biliary duct injury is a common complication in laparoscopic procedure. Operating time is more in case of laparoscopic cholecystectomy group.