Aim: Work-related musculoskeletal disorders consist of group of symptoms caused by occupational risk factors. These symptoms are the main cause of loss of productive working time and increase in labor costs. This study aims at estimating the prevalence and identifying risk factors for developing work-related musculoskeletal symptoms in surgeons performing laparoscopic surgery. Materials and methods: This cross-sectional study was conducted on 50 surgeons in a tertiary care hospital of Ahmedabad. In this study, the prevalence and severity of musculoskeletal symptoms was evaluated using the Nordic Pain questionnaire and Workplace Ergonomic Risk Assessment (WERA) method in surgeons performing laparoscopic surgery. Results and conclusion: The results revealed that there's development of significant pain during laparoscopic surgeries due to various reasons like neck posture and shoulder abduction posture; various ergonomics of laparoscopy. Workplace Ergonomic Risk Assessment scoring was very effective in identifying group of surgeons having high risk of developing musculoskeletal symptoms. This study concluded that surgeons maintained a more extended posture during laparoscopic surgery that led to musculoskeletal symptoms.