Though laparoscopic salpingotomy is the preferred conservative surgery of choice in patients desirous of future fertility, the management of ectopic pregnancy has changed extensively. Other modalities like medical management with Methotrexate are being reviewed for conservative management of tubal pregnancy.
To compare intratubal Methotrexate instillation with laparoscopic salpingotomy for conservative management of tubal pregnancy.
A literature review was conducted using search engines Google, Highwire press. Success rate after treatment and future reproductive outcome were analyzed.
Laparoscopic salpingotomy was more superior to with Methotrexate as conservative treatment of ectopic pregnancy.
Predictive value of history and physical examination in patients with suspected ectopic pregnancy. Ann Emerg Med 1999;33:283-90.
Accuracy of clinical diagnostic methods of threatened abortion. Gynecol Obstet Invest 2003;56:38-42.
Should patients who are suspected of having an ectopic pregnancy undergo physical examination? Fertil Steril 1999;71:155-57.
Ultrasound availability in the evaluation of ectopic pregnancy in the ED: Comparison of quality and cost-effectiveness with different approaches. Am J Emerg Med 2000;18:408-17.
Medical management of tubal pregnancy. Number 3.
Clinical management guidelines for obstetriciansgynecologists. Int J Gynaecol Obstet 1999;65:97-103.
Clinical policy: Critical issues in the initial evaluation and management of patients presenting to the emergency department in early pregnancy. Ann Emerg Med 2003;41:123-33.
Management of ectopic pregnancy. Am Farm Physician 1990;41:1215-22.
New options for diagnosis and treatment of ectopic pregnancy. JAMA 1992;267:534-37.
Advances in diagnosis and treatment of ectopic pregnancy during the past ten years. Zhonghu Fu Chan Ke Za Zhi Jul 2000;35(7):408-10.
Medical therapy for ectopic pregnancy. Semin Reprod Med Mar 2007;25(2):93-98.
Papantoniou, John S. Papageorgiou, Stylianos K. Michalas. Local Application of Methotrexate.
Randomized trial of conservative laparoscopic treatment and methotrexate administration in ectopic pregnancy and subsequent fertility. Human Reproduction 1998;13(11):3239-43.
Limited role for intratubal methotrexate treatment of ectopic pregnancy. Fertil Steril Jan1995;63(1):20-24.
Intra amniotic Methotrexate versus CO2 laser laparoscopic salpingotomy in the management of tubal ectopic pregnancy a prospective randomized trial. Fertility and Sterility 1994;62:876-78.
Comparison of local methotrexate and linear salpingostomy in the conservative laparoscopic treatment of ectopic pregnancy. Journal of the American Association of Gynecologic Laparoscopists 1996;3:271-76.
Ultrasound guided injection of methotrexate versus laparoscopic salpingotomy in ectopic pregnancy. Fertility and Sterility 1995;63:25-29.
Laparoscopic salpingostomy versus laparoscopic local methotrexate injection in the management of unruptured ectopic gestation. American Journal of Obsterics and Gynecology 1996;175:600-02.
D Clinical and financial analyses of ectopic pregnancy management at a large health plan. Obstet Gynecol 1997;4:207-13.
Treatment of the small unruptured ectopic pregnancy: A cost analysis of methotrexate versus laparoscopy. Obstet Gynecol 1996;88:123-27.
Clinical and financial analyses of ectopic pregnancy management at a large health plan. J Am Assoc Gynecol Laparosc 1997;4:207-13.