World Journal of Laparoscopic Surgery with DVD

Register      Login

VOLUME 6 , ISSUE 1 ( January-April, 2013 ) > List of Articles

REVIEW ARTICLE

What Should be the Approach in the Long-term Management of Patients with Gastroesophageal Reflux Disease?

Mohamed Solih

Citation Information : Solih M. What Should be the Approach in the Long-term Management of Patients with Gastroesophageal Reflux Disease?. World J Lap Surg 2013; 6 (1):23-28.

DOI: 10.5005/jp-journals-10033-1176

Published Online: 01-04-2013

Copyright Statement:  Copyright © 2013; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Objective

The aim of this study is to review available treatment options and to review current opinions in the management of patients with chronic gastroesophageal reflux disease (GERD).

Materials and methods

This is a review article. Articles for the literature review were collected by using Google Search Scholar Engine. Literature search included relevant original and review articles addressing issues like medical treatment for GERD, surgical treatment for GERD, studies comparing surgical and medical treatment for GERD.

GERD is a common and chronic syndrome. Patients affected with syndrome experience symptoms which affect their quality of life.

The goals of treatment in this condition is to control symptoms, heal injured esophageal mucosa and to prevent complications. Both proton pump inhibitor (PPI) therapy and antireflux surgery are equally effective in controlling symptoms and in healing esophageal mucosal injury. In the recent years, laparoscopic surgery is increasingly been offered to patients with GERD. However, there is still controversy over best approach to management of GERD. This study attempted to review current opinions of this issue.

Conclusion

PPIs is an option for initial management of GERD. However, this condition been a chronic condition, relapse is common while on therapy with medications or following discontinuation of therapy. Hence, a treatment option which provides effective control of symptoms and prevents or minimizes complications has to be offered to patients. Medical therapy with PPI and laparoscopic antireflux surgery, both can achieve these therapeutic goals. Hence, in the light of this literature review it is recommended to individualize the treatment offered to the patient with GERD, in consultation with the patient himself or herself.

How to cite this article

Solih M. What Should be the Approach in the Long-term Management of Patients with Gastroesophageal Reflux Disease? World J Lap Surg 2013;6(1): 23-28.


PDF Share
  1. American gastroenterological association medical position statement on the management of gastroesophageal reflux disease. Gastroenterology 2008;135:1383-91.
  2. Symptomatic gastroesophageal reflux: Incidence and precipitating factors. Am J Dig Dis 1976;21(11):953-56.
  3. Patterns of gastroesophageal reflux in health and disease. Annals Surg 1976;184(4):459-70.
  4. Epidemiology and natural history of reflux disease. Baillieres Best Pract Res Clin Gastroenterol 2000;14(5):743-57.
  5. Whistle summary: The slow rate of rapid progress. J Clin Gastroenterol 2007;41(6):539-45.
  6. Mechanisms of action of antireflux surgery: Theory and fact. World J Surg 1992;16:320-25.
  7. Mechanisms underlying the antireflux action of fundoplication. Gut 1993;34:303-08.
  8. The frontiers of reflux disease. Dig Dis Sci 2006;51(11):1887-95.
  9. Acid suppression in the long-term treatment of peptic strictures in Barrett's oesophagus. Digestion 1992;51(suppl 1):49-58.
  10. Laparoscopic Nissen fundoplication: Preliminary report. Surg Laparosc Endosc 1991;1(3):138-43.
  11. Antireflux surgery in the laparoscopic era. Br J Surg 1998;85:1173-84.
  12. Complications and results of primary minimally invasive antireflux procedures: A review of 10, 735 reported cases. J Am Coll Surg 2001;193:428-39.
  13. Effects of sleeping with the bed-head raised and of ranitidine in patients with severe peptic oesophagitis. The Lancet 1987;2(8569):1200-03.
  14. Proton pump inhibitors or histmine 2 receptor antagonists for the prevention of recurrences of erosive esophagitis: A cost effectiveness analysis. Am J Gastroenterol 92(12):2179-87.
  15. Proton pump inhibitors and acid-related diseases. Pharmacotherapy 17(1):22-37.
  16. The proton-pump inhibitors: Similarities and differences. Clin Ther 22(2):266-80.
  17. Omeprazole 10 mg once daily, omeprazole 20 mg once daily or ranitidine 150 mg twice daily, evaluated as initial therapy for the relief of symptoms of gastroesophageal reflux disease in general practice. Scand J Gastroenterol 1997;32:965-73.
  18. Short-term treatment with proton pump inhibitors, H2- receptor antagonists and prokinetics for gastroesophageal reflux disease-like symptoms and endoscopy negative reflux disease. Cochrane Database Syst Rev 2006;3:CD002095.
  19. Gatroeshophageal reflux disease: Medical or surgical treatment? Gastroenterol Res Prac 2009;10;1-15.
  20. Proton pump inhibitor failure—what are the therapeutic options? Am J Gastroenterol 2009;104:S33-38.
  21. Comparison of risk factors and clinical responses to proton pump inhibitors in patients with erosive oesophagitis and nonerosive reflux disease. Aliment Pharmacol Ther 30(2):154-64.
  22. Medical treatments for the maintenance therapy of reflux esophagitis and endoscopic negative reflux disease. Cochrane Database Sys Rev 2010;2:CD003245.
  23. Long-term safety concerns with proton pump inhibitors. Am J of Med 2009;122:896-903.
  24. Use of proton pump inhibitors and risk of osteoporosis-related fratures. CMAJ 179(4):306-07.
  25. Evidence based appraisal of antireflux fundoplication. Annals Surg 239(3):325-37.
  26. Comparing laparoscopic antireflux surgery with esomeprazole in the management of patients with chronic gastroesophageal reflux disease: A 3 years interim analysis of the LOTUS trial. GUT 2008;57:1207-13.
  27. Laparoscopic fundoplication. Gastroesophageal Reflux Disease 2006;173-82.
  28. Comparative results of endoluminal gastroplasty and laparoscopic antireflux surgery for the treatment of GERD. Surg Endosc 18(2):261-65.
  29. A novel endoscopic fullthickness plicator for the treatment of GERD: A pilot study. Gastrointest Endosc 58(5):452-512.
  30. Long-term efficacy of total (Nissen Rossetti) and posterior partial (Toupet) fundoplication: Results of a randomized clinical trial. J Gastrointest Surg 6(4):540-45.
  31. Dysphagia after laparoscopic antireflux surgery: The impact of operative technique. Annals Surg 1996;224(1):51-57.
  32. Seven years follow-up of a randomized clinical trial comparing proton-pump inhibition with surgical therapy for reflux oesophagitis. Br J Surg 2007;94(2):198-203.
  33. Clinical results of laparoscopic fundoplication at 10 years after surgery. Surg Endosc 2006;20(1):159-65.
  34. Nissen vs Toupet laparoscopic fundoplication: A prospective randomized study of 200 patients with and without preoperative esophageal motility disorders. Surg Endosc 2002;16(5):758-66.
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.