World Journal of Laparoscopic Surgery

Register      Login

VOLUME 7 , ISSUE 3 ( September-December, 2014 ) > List of Articles

RESEARCH ARTICLE

Remission of Type 2 Diabetes Mellitus after Laparoscopic Sleeve Gastrectomy

Salman Al-Sabah, Sulaiman Almazeedi, Sameer Alosaimi, Ahmed Al-Mulla, Daliya Al-Mohammad Ali, Abdullah Al-Elewah, Ardavan Algooneh

Citation Information : Al-Sabah S, Almazeedi S, Alosaimi S, Al-Mulla A, Ali DA, Al-Elewah A, Algooneh A. Remission of Type 2 Diabetes Mellitus after Laparoscopic Sleeve Gastrectomy. World J Lap Surg 2014; 7 (3):121-124.

DOI: 10.5005/jp-journals-10033-1231

Published Online: 00-12-2014

Copyright Statement:  Copyright © 2014; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Introduction

Type 2 diabetes mellitus (T2DM) comprises 90% of diabetics and is largely the result of excess body weight. There is rising evidence in the literature to suggest that laparoscopic sleeve gastrectomy (LSG) produces effective weight loss and improves obesity-related comorbidities, such as T2DM. The purpose of the study is to observe the effectiveness of LSG in the remission of T2DM.

Materials and methods

A retrospective study of 107 diabetic obese patients who underwent LSG at Alamiri Hospital, from October 2008 to 2012 was conducted. The pre- and postoperative diabetic status, body mass index, and percent excess weight loss (%EWL) of the patients were retrieved and analyzed.

Results

The mean age of the patients was 42 years ± 10.4 and 68% were females. Median preoperative BMI was 46 kg/m2 (30-87) and median postoperative follow-up period was 18 (2-48) months. Pre- and postoperative fasting blood glucose and HbA1C were measured. Resolution and improvement of T2DM was 53.3% (n = 57) and 38.3% (n = 41), respectively. The %EWL was 72% at 1 year and 73% at 4 years and median postoperative BMI was 33 kg/m2 (20-61). Duration based analysis showed that most of the resolved patients had diabetes for less than 5 years.

Conclusion

LSG resulted in total remission of T2DM in more than half of the patients and is more effective for the treatment of patients with short-term duration of the disease.

How to cite this article

Al-Sabah S, Almazeedi S, Alosaimi S, Al-Mulla A, Ali DA, Al-Elewah A, Algooneh A. Remission of Type 2 Diabetes Mellitus after Laparoscopic Sleeve Gastrectomy. World J Lap Surg 2014;7(3):121-124.


PDF Share
  1. Obesity and overweight factsheet [WHO website]. March 2013. Available at: http://www.who.int/mediacentre/factsheets/fs311/en/index.html.Accessed on October 2013.
  2. Health hazards associated with obesity in adults [up-to-date website]. Feb 5, 2013. Available at: http://www.uptodate.com/contents/health-hazards-associated-withobesity- in-adults. Accessed October 13, 2013.
  3. lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery. N Engl J Med 2004;351(26):2683-2693.
  4. Bariatric surgery: an IDF statement for obese type 2 diabetes. Diabet Med 2011;28(6):628-642.
  5. Impact of laparoscopic sleeve gastrectomy and laparoscopic gastric bypass on hba1c blood levels and pharmacological treatment of type 2 diabetes mellitus in severe of morbidly obese patients. results of a multicenter prospective study at 1 year. Obes Surg 2011;21(6):738-743.
  6. Sleeve gastrectomy and type 2 diabetes mellitus: a systemic review. Surg Obes Relat Dis 2010;6(6):707-713.
  7. Long-term effects of laparoscopic sleeve gastrectomy, gastric bypass, and adjustable gastric banding on type 2 diabetes. Surg Endosc 2010;24(5):1005-1010.
  8. Laparoscopic sleeve gastrectomy for diabetes treatment in nonmorbidly obese patients: efficacy and change of insulin secretion. Surgery 2010;147(5):664-669.
  9. Impact of laparoscopic sleeve gastrectomy and laparoscopic gastric bypass on HbA1c blood level and pharmacological treatment of type 2 diabetes mellitus in severe or morbidly obese patients. Results of a multicenter prospective study at 1 year. Obes Surg 2011;21(6):738-743.
  10. Comparison of comorbidity resolution and improvement between laparoscopic sleeve gastrectomy and laparoscopic adjustable gastric banding. Surg Endosc 2010;24(10):2513-2517.
  11. Short-term effects of sleeve gastrectomy on type 2 diabetes mellitus in severely obese subjects. Obes Surg 2007;17(8):1069-1074.
  12. Bariatric surgery versus intensive medical therapy in obese patients with diabetes. N Engl J Med 2012;366(17):1567-1576.
  13. Type 2 diabetes after gastric bypass: remission in five models using HbA1C, fasting blood glucose, and medication status. Surg Obes Relat Dis 2012;8(5):548-555.
  14. Remission of type 2 diabetes after gastric bypass and banding: mechanisms and 2 year outcomes. Ann Surg 2010;252(6):966-971.
  15. Roux-en-Y gastric bypass vs sleeve gastrectomy for obese patients with type 2 diabetes: a randomized trial. Diabetologia 2013;56(9):1914-1918.
  16. Improvement in glucose metabolism after bariatric surgery: comparison of laparoscopic roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy. Ann Surg 2009;250(2):234-241.
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.