Aim: Our aim was to study the feasibility of a laparoscopic approach in the management of polypoidal lesions of the stomach. Materials and methods: We present a review of laparoscopic management in polypoidal lesions of the stomach in four patients. All patients underwent routine preoperative workup along with esophagogastroduodenoscopy, biopsy, and contrast-enhanced computed tomography (CECT) scan of the abdomen. Three patients underwent wedge resection of the stomach using a laparoscopic linear stapler and one underwent laparoscopic anterior wall gastrotomy with polypectomy. Results: Of four patients, three were males and one was female in the age range of 40–60 years. Presenting symptoms ranged from generalized weakness, episodes of intermittent vomiting, dyspepsia, and weight loss. Common sites involved were fundus and body of the stomach in three patients and antrum in one patient. Surgery via a laparoscopic approach was the mainstay of the treatment. Final histopathology revealed gastrointestinal stromal tumor (GIST) in three patients and adenomatous polyp in one patient. Patients diagnosed with GIST were further referred to a medical oncologist for mutational analysis and adjuvant therapy. All patients are on regular follow-up postoperatively. Conclusion: Asymptomatic, polypoidal lesions of the stomach can present with occult GI bleeding or gastric outlet obstruction. The main point to be taken into consideration in treating large-sized polyps is the selection of management option (endoscopic vs laparoscopic). Laparoscopic excision is a better alternative to treat giant polyps considering the size, location, and potential for malignancy, as opposed to an endoscopic approach.