Keywords :
Antisepsis, Hand wash, Povidone-iodine, Scrub
Citation Information :
Sridhar L, Phadnis R, Tiruchirapalli KS, Hussain F, Kurumella SN, Chappidi SC. The Ideal Hand Hygiene Method in the Age of Water Scarcity: A Systematic Review and Meta-analysis. World J Lap Surg 2024; 17 (3):157-163.
In modern times, surgical site infections (SSIs) are defined as infections occurring within 30 days after surgery (or 1 year in patients with implants) at the incision or deep tissue level. Purulent drainage should be observed and organisms from the site should be isolated for epidemiological purposes. Most of the factors contributing to SSIs are patient-related, as the majority of infections are caused by endogenous flora. It has also been suggested that unclean operating hands due to glove contamination do not affect rates of postoperative infections. While the traditional surgical scrub has so far stood the test of time, it is important to consider its environmental impact. There have been multiple attempts to reduce the carbon footprint of the surgical hand scrub, including usage of a different model of tap but there is an easier option available to us: hand rubbing. It takes up significantly less water, as reported by some of the studies given above. It is also particularly beneficial in resource-limited settings. All studies except one reported that hand rub solutions are also more affordable, making them accessible in poorer countries and hospitals. Our study results similarly suggest that waterless hand rubbing is at least as effective as hand scrubbing in preventing SSIs, and is a viable solution to address water scarcity concerns.
Tyagi U, Barwal KC. Ignac Semmelweis–Father of hand hygiene. Indian J Surg 2020;82(3):276–277. DOI: 10.1007/s12262-020-02386-6.
Lane HJ, Blum N, Fee E. Oliver Wendell Holmes (1809–1894) and Ignaz Philipp Semmelweis (1818–1865): Preventing the transmission of puerperal fever. Am J Public Health 2010;100(6):1008–1009. DOI: 10.2105/AJPH.2009.185363
Holmes OW. Puerperal Fever as a Private Pestilence. Boston, MA: Ticknor and Fields; 1855. Available from: http://resource.nlm.nih.gov/67241040R.
Semmelweis IF. Die Ätiologie, der Begriff und die Prophylaxis des Kindbettfiebers. Pest: Hartleben; 1961. Available from: https://www.jameslindlibrary.org/semmelweis-i-1861/.
Lister J. On the antiseptic principle in the practice of surgery. Br Med J 1867;2(351):246–248. DOI: 10.1136/bmj.2.351.246.
Zabaglo M, Sharman T. Postoperative Wound Infection. [Updated 2022 Sep 19]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023.
Young PY, Khadaroo RG. Surgical site infections. Surg Clin North Am 2014;94(6):1245–1264. DOI: 10.1016/j.suc.2014.08.008.
Litofsky NS, Cohen D, Schlesselman C, et al. No link between inadvertent surgical glove contamination and surgical site infection in patients undergoing elective neurosurgical operations. World Neurosurg 2023;175:e1025–e1031. DOI: 10.1016/j.wneu.2023. 04.065.
Spirling LI, Daniels IR. William Stewart Halsted–surgeon extraordinaire: a story of ‘drugs, gloves and romance’. J R Soc Promot Health 2002;122(2):122–124. DOI: 10.1177/146642400212200215.
Thomas S, Agarwal M, Mehta G. Intraoperative glove perforation–Single versus double gloving in protection against skin contamination. Postgrad Med J 2001;77(909):458–460. DOI: 10.1136/pmj.77.909.458.
Suchomel M, Brillmann M, Assadian O, et al. Chlorhexidine-coated surgical gloves influence the bacterial flora of hands over a period of 3 hours. Antimicrob Resist Infect Control 2018;7:108. DOI: 10.1186/s13756-018-0395-0.
Apollo Hospitals 2023. A Day in the Life at Apollo accessed on September 12, 2023. Available from: https://www.apollohospitals.com/corporate/company-overview/the-apollo-story/milestones/a-day-at-apollo/.
Ahmed A. Surgical hand scrub: Lots of water wasted. Ann Afr Med 2007;6(1):31–33. DOI: 10.4103/1596-3519.55733.
Jehle K, Jarrett N, Matthews S. Clean and green: Saving water in the operating theatre. Ann R Coll Surg Engl 2008;90(1): 22–24. Available from: https://doi.org/10.1308/003588408x242277.
UNU-INWEH: Global Water Security 2023 Assessment. 2023. Available from: https://www.unwater.org/news/unu-inweh-global-water-security-2023-assessment.
Singh AK. Water security – A reality check. Journal of the International Journal of Plant & Soil Science 2018;66:179–192. Available from: https://www.researchgate.net/publication/354497160_Water_Security_-A_Reality_Check.
World Health Organization. WHO guidelines on hand hygiene in health care 2009. pp. 270.
Haddaway NR, Page MJ, Pritchard CC, et al. PRISMA2020: An R package and Shiny app for producing PRISMA 2020-compliant flow diagrams, with interactivity for optimised digital transparency and Open Synthesis. Campbell Systematic Reviews 2022;18(2):e1230. Available from: https://doi.org/10.1002/cl2.1230.
Parienti JJ, Thibon P, Heller R, et al. Hand-rubbing with an aqueous alcoholic solution vs traditional surgical hand-scrubbing and 30-day surgical site infection rates: A randomized equivalence study. JAMA 2002;288(6):722–727. DOI: 10.1001/jama.288.6.722.
Al-Naami MY, Anjum MN, Afzal MF, et al. Alcohol-based hand-rub versus traditional surgical scrub and the risk of surgical site infection: A randomized controlled equivalent trial. EWMA J 2009; 9(3)5–10.
Gaspar GG, Menegueti MG, Lopes AER, et al. Alcohol-based surgical hand preparation: Translating scientific evidence into clinical practice. Antimicrob Resist Infect Control 2018;7:80. DOI: 10.1186/s13756-018-0372-7.
Nthumba PM, Stepita-Poenaru E, Poenaru D, et al. Cluster-randomized, crossover trial of the efficacy of plain soap and water versus alcohol-based rub for surgical hand preparation in a rural hospital in Kenya. Br J Surg 2010;97(11):1621–1628. DOI: 10.1002/bjs.7213.
Iwakiri K, Kobayashi A, Seki M, et al. Waterless hand rub versus traditional hand scrub methods for preventing the surgical site infection in orthopedic surgery. Spine (Phila Pa 1976). 2017;42(22):1675–1679. DOI: 10.1097/BRS.0000000000002200.
Adjoussou S, Konan Blé R, Séni K, et al. Intérêt de la désinfection chirurgicale des mains par friction alcoolique en milieu tropical [Value of hand disinfection by rubbing with alcohol prior to surgery in a tropical setting]. Med Trop (Mars) 2009;69(5):463–466. PMID: 20025174.
Chen CF, Han CL, Kan CP, et al. Effect of surgical site infections with waterless and traditional hand scrubbing protocols on bacterial growth. Am J Infect Control 2012;40(4):e15–e17. DOI: 10.1016/j.ajic.2011.09.008.
Vergara-Fernández O, Morales-Olivera JM, Ponce-de-León-Rosales S, et al. Niveles de satisfacción del equipo quiúirgico entre dos métodos de lavado de mano [Surgical team satisfaction levels between two preoperative hand-washing methods]. Rev Invest Clin 2010;62(6):532–537. PMID: 21416914.
Murie JA, Macpherson SG. Chlorhexidine in methanol for the preoperative cleansing of surgeons’ hands: A clinical trial. Scott Med J 1980;25(4):309–311. DOI: 10.1177/003693308002500413.
Weight CJ, Lee MC, Palmer JS. Avagard hand antisepsis vs. traditional scrub in 3600 pediatric urologic procedures. Urology 2010;76(1):15–17. DOI: 10.1016/j.urology.2010.01.017.
Oriel BS, Chen Q, Itani KM. The impact of surgical hand antisepsis technique on surgical site infection. Am J Surg 2017;213(1):24–29. DOI: 10.1016/j.amjsurg.2016.09.058.
Rubio PA. Septisol antiseptic foam: A sensible alternative to the conventional surgical scrub. Int Surg 1987;72(4):243–246. PMID: 3448039.
Deeks JJ, Higgins JPT, Altman DG (editors). Chapter 10: Analysing data and undertaking meta-analyses. In: Higgins JPT, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (editors). Cochrane Handbook for Systematic Reviews of Interventions version 6.4 (updated August 2023). Cochrane, 2023. Available from: www.training.cochrane.org/handbook.
Higgins JPT, Altman DG, Sterne JAC (editors). Chapter 8: Assessing risk of bias in included studies. In: Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions version 6.4 (updated August 2023). Cochrane, 2023. Available from: www.training.cochrane.org/handbook.
Kramer A, Hübner N, Below H, et al. Improving adherence to surgical hand preparation. J Hosp Infect 2008;70(Suppl 1):35–43. DOI: 10.1016/S0195-6701(08)60009-2.
Owens CD, Stoessel K. Surgical site infections: Epidemiology, microbiology and prevention. J Hosp Infect 2008;70(Suppl 2):3–10. DOI: 10.1016/S0195-6701(08)60017-1.
Hobson DW, Woller W, Anderson L, et al. Development and evaluation of a new alcohol-based surgical hand scrub formulation with persistant anti-microbial characteristics and brushless application. Am J Infect Control 1998;26(5):507–512. DOI: 10.1016/s0196-6553(98)70024-0.
Larson EL, Butz AM, Gulette DL, et al. Alcohol for surgical scrubbing? Infect Control Hosp Epidemiol 1990;11(3):139–143. DOI: 10.1086/646137.
Reybouck G. Handwashing and hand disinfection. J Hosp Infect 1986;8(1):5–23. DOI: 10.1016/0195-6701(86)90100-3.
Pereira LJ, Lee GM, Wade KJ. An evaluation of five protocols for surgical handwashing in relation to skin condition and antimicrobial counts. J Hosp Infect 1997;36(1):49–65. DOI: 10.1016/s0195-6701(97)90090-6.
Ayliffe GAJ, Babb JR, Davis JC, et al. Hand disinfection: A comparison of various agents in laboratory and wards studies. J Hosp Infect 1988;11(3):226–243. DOI: 10.1016/0195-6701(88)90101-6.
Hosseini P, Mundis GM Jr, Eastlack R, et al. Do longer surgical procedures result in greater contamination of surgeons’ hands? Clin Orthop Relat Res 2016;474(7):1707–1713. DOI: 10.1007/s11999-016-4832-1.
Ho YH, Wang YC, Loh EW, et al. Antiseptic efficacies of waterless hand rub, chlorhexidine scrub, and povidone-iodine scrub in surgical settings: A meta-analysis of randomized controlled trials. J Hosp Infect 2019;101(4):370–379. DOI: 10.1016/j.jhin.2018.11.012.
Boyce JM, Kelliher S, Vallande N. Skin irritation and dryness associated with two hand-hygiene regimens: Soap-and-water hand washing versus hand antisepsis with an alcoholic hand gel. Infect Control Hosp Epidemiol 2000;21(7):442–448. DOI: 10.1086/501785.
Batalla A, García-Doval I, de la Torre C. Productos de higiene y antisepsia de manos: Su empleo y relación con el eccema de manos en los profesionales sanitarios [Products for hand hygiene and antisepsis: Use by health professionals and relationship with hand eczema]. Actas Dermosifiliogr 2012;103(3):192–197. DOI: 10.1016/j.adengl.2012.04.004.
García-Gavín J, Pérez-Pérez L, Zulaica A. Hand eczema due to hygiene and antisepsis products: not only an irritative etiology. Actas Dermosifiliogr 2012;103(9):845–846. DOI: 10.1016/j.adengl.2012.06.019.
Mulberrry G, Snyder AT, Heilman J, et al. Evaluation of a waterless, scrubless chlorhexidine gluconate/ethanol surgical scrub for antimicrobial efficacy. Am J Infect Control 2001; 29(6):377–382. DOI: 10.1067/mic.2001.118842.
Hajipour L, Longstaff L, Cleeve V, et al. Hand washing rituals in trauma theatre: Clean or dirty? Ann R Coll Surg Engl 2006;88(1):13–15. DOI: 10.1308/003588406X83032.
Kampf G, Kramer A, Suchomel M. Lack of sustained efficacy for alcohol-based surgical hand rubs containing ‘residual active ingredients’ according to EN 12791. J Hosp Infect 2017;95(2):163–168. DOI: 10.1016/j.jhin.2016.11.001.
Kampf G. Lack of antimicrobial efficacy of mecetronium etilsulfate in propanol-based hand rubs for surgical hand disinfection. J Hosp Infect 2017;96(2):189–191. DOI: 10.1016/j.jhin.2017.03.001.
Wilkinson MAC, Ormandy K, Bradley CR, et al. Comparison of the efficacy and drying times of liquid, gel and foam formats of alcohol-based hand rubs. J Hosp Infect 2018;98(4):359–364. DOI: 10.1016/j.jhin.2017.09.024.
Somner JE, Stone N, Koukkoulli A, et al. Surgical scrubbing: Can we clean up our carbon footprints by washing our hands? J Hosp Infect 2008;70(3):212–215. DOI: 10.1016/j.jhin.2008.06.004.