VOLUME 18 , ISSUE 1 ( January-April, 2025 ) > List of Articles
Veronica Vecchio, Eva Intagliata, Rossella Rosaria Cacciola, Emma Cacciola, Rosario Vecchio
Keywords : Hemocoagulation, Liver cirrhosis, Subtotal laparoscopic cholecystectomy
Citation Information : Vecchio V, Intagliata E, Cacciola RR, Cacciola E, Vecchio R. Hemocoagulative Considerations on Laparoscopic Cholecystectomy in Patients with Liver Cirrhosis. World J Lap Surg 2025; 18 (1):51-52.
DOI: 10.5005/jp-journals-10033-1646
License: CC BY-NC 4.0
Published Online: 16-12-2024
Copyright Statement: Copyright © 2025; The Author(s).
A still debated issue is how to treat gallbladder diseases in patients with advanced stages of liver cirrhosis. Laparoscopic cholecystectomy has specific advantages in patients with liver cirrhosis. Complications of the wound, incisional hernia rate, operating time, and hospitalization time are significantly reduced due to the less invasiveness of laparoscopic cholecystectomy. The risk of contamination of the ascitic fluid and the exposure of the surgical team to fluids infected by hepatitis C virus (HCV) or hepatitis B virus (HBV) are reduced. The risk of bleeding is also reduced, either because of the less invasiveness of the procedure or the pneumoperitoneum pressure, which induces vascular compression. There is another important reason that can help reduce bleeding during laparoscopic cholecystectomy in cirrhotic patients. Laparoscopic surgery induces activation of coagulation and fibrinolytic pathways. This prothrombotic tendency may be a further advantage for cirrhotic patients who tend to have alterations of coagulation in a prohemorrhagic sense.
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